MODELING OF IONIZING RADIATION-INDUCED CHROMOSOME ABERRATION AND TUMOR PREVALENCE BASED ON TWO CLASSES OF DNA DOUBLE-STRAND BREAKS CLUSTERING IN CHROMATIN DOMAINS

There has been some controversy over the use of radiobiological models when modeling the dose-response curves of ionizing radiation (IR)-induced chromosome aberration and tumor prevalence, as those curves usually show obvious non-targeted effects (NTEs) at low doses of high linear energy transfer (LET) radiation.The lack of understanding the contri

In this paper, a physics-based model that couples a bank erosion model with a meander evolution model is developed and evaluated.The physics-based bank erosion model considers the cantilever failure mechanism with slump blocks and decomposition effects.Moreover, bank accretion was considered Miscellaneous using critical values of time required for

Essential oils (EOs) have been used in ethno-medicine as an effective and safe antimicrobial agents for a long time.They have been evaluated for the bactericidal, fungicidal, antiparasitical, insecticidal, virucidal, medicinal and cosmetics applications.EOs are derived from various species of edible and medicinal plants including herbs and spices.T

Adenosine is a metabolite produced abundantly in the tumor microenvironment, dampening immune response in inflamed tissues via adenosine A2A receptor (A2AR) which is widely expressed on 2A immune cells, inhibiting anti-tumor immune response accordingly.Therefore, blocking adenosine signaling pathway is of potential to promote anti-tumor immunity.Th

Introduction Embitterment is an emotion which is known to everybody in reaction to injustice, humiliation, and breach of trust.In greater intensity it can cause severe suffering for the affected person and the social envirnment, can result in lasting impairment, and even lead to dysfunctional behavior, including aggression.Embittered patients need